While I totally understand the engineering benefits of a total chassis swap I'm not a fan of the method. To me, once you're all done you've got a '91 Dakota with a '37 Dodge body grafted on vs having a '37 Dodge with a new driveline. I can't really say why it carries that stigma for me, because no one seems to be bothered by a resto-mod '55 Chevy sitting on an Art Morrison chassis, but that chassis is custom made to fit that body and is much cleaner than the OEM frame. There's a big following of S10 chassis grafted under vehicles of all shapes and sizes, but it's just not for me. The method (late model chassis, old body) is very popular in New Zealand, but there it gets one past a ton of the regulations, inspections and approvals of a one-off chassis build, unless you're a retired dairy farmer from Rahotu

If the original chassis is good I'd look at grafting on a front and rear suspension of choice along with a new power train, but to each his own. Either way you'll have an unusual car not often seen re-done. Looking forward to watching the build, no matter how you go with it.