New info update:

I checked a dozen websites and made several long distance phone calls. Here's what I found...

For a 48-52 Ford F1 pick-up:

You can swap 48 to early 60s F1/F100, 11" front hubs/drums.
BUT, you've got to do it as a hub and drum set.

You CANNOT mix-n-match one years hub with another years drum because of the OFFSET/BACKSPACE.

Too much offset and the drum won't meet the backing plate. Too much backspacing and the drum slams against the backing plate and wont meet the hub.

The fit of the hub to the spindle is determined by the Wheel bearings.