Just a small suggestion, you might want to try to keep your questions in pretty much the same post so it's easier to keep track of the answers you get.

As far as the 460, it would help to know what year the engine is and what the casting number on the heads are so we know what you are starting with.

I'm assuming from your posts so far that the PRIMARY duty of the car will be as a cruiser, so I think I would concentrate on that first and let the 1/4 mile times take care of themselves.

I general, I would keep the compression down to about 9.0 to 1 and would look for parts that make power in the 2000-5500 RPM range (making these engines wind up past that gets a little pricey as far as building a bottom end that will hold together).

Concentrate on building a strong bottom end with quality parts and include things like magnafluxing and resizing the rods if necessary new rod bolts etc and balancing the rotating assembly.

If your planning on a nitros shot, I would suggest forged pistons (although with this torque monster I would see how it ran before I put NOS on).

As with many of the Fords, the 460 (depending on the heads) are pretty restrictive on the exhaust side. One cure for this would be an aftermarket set of aluminum heads. At a minimum a dual pattern cam biased to the exhaust should be used.

I would top it off with a good dual plane intake a set of headers and at least a 750 CFM carb.

If the body permits it, I would use a rear sump pan and pickup to prevent oil starvation under acceleration, or at a minimum a well baffeled pan if you have to run a front sump.

A stout C6 should hold up behind the engine.

The car likely already has a 9". With the torque the motor should make and the relatively low RPM I would be conservitive on the gears somewhere in the 3.25 to 3.55 range, and no deeper than 4.11. A good source for gears other than the aftermarket are Ford truck and Vans.

With all that done your biggest problem will likely be getting it to hook up.