Depends on what you build. Most pickups have a fairly stout frame, however they're held together with rivets so best to weld them to get the flex out... I much prefer the IFS front ends, but make sure it's got tubular A-Arms and not the OEM stamped steel junk... Wheelbase and body design have a lot to do with how the rest of the frame is designed, best to have the body you are going to use before starting on a chassis.