Richard, employing the white cat is a good start. Cats scare the mice and rats off, so once the nests are cleaned out no worries about reinfestation!
I think it would be cool if it fit on the s10 frame. Lots of guys here seem to use them, and there are a lot of inexpensive s10's to be had. It would simplify a lot of stuff mechanically. She sure looks like a big truck though! Maybe a beefier frame from a 1500 or 2500 might be in order. Just a thought.