Would disabling the secondaries be a workable option? I know the orientation of the carb barrels sitting one-over-each-port would not exist, but it has a large plenum, which would help. Maybe a pair of 600s or bigger, since many carbs have smaller primary bores.

I know I have run a single 660 center squirter on a hipo 327 with success, but the manifold also had a large plenum.