Thread: Gen.VI 454 build

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Hey guys, new to the site and was looking for some help on a Gen VI big-block build.
The motor in my 99 K2500 crew cab (Gen VI 454) developed an ugly knock, I found a good deal on replacement with only 20k on it.To the best of my knowledge, the new motor is a factor long block, with no additional work done to it. Before I swap the motors, I was thinking about making a few upgrades like cam and springs. I can find lots of info on massive hp builds, but not much in the way of daily driver builds. Any help would be greatly appreciated!

Any thoughts on cam and spring upgrades?
Plan on keeping fuel injection..is that a bad idea?
Will I need a new tune if I change cam and springs?
Any other thoughts would be greatly appreciated!
Thanks