If you mean seat of the pants noticeable, no it wont...but it will give you slightly better times at the races. The bigger intake valve will likely help at higher rpms, but the heads flow surprisingly well at low and mid rpms, as in street driving, with the stock valves. But with the combo you're proposing, I would install the larger valves. The problem with the larger intake and the smaller bore is going to be shrouding around the intake valve. That's one argument for sticking with the smaller valve.