I've painted every place except outdoors, or with a dirt floor. Never had a great booth yet, but since I've learned to control the air and dust, wet the floor, and sand & buff every job. I've been able to produce show quality work when needed. My first car was painted in my grandpa's garage. :-)

Just be sure you aren't exposing your paint fumes to an open flame or spark. Also,
the faster you can move the air out of the booth, the less the chance of problems.