Obviously at 10:1 you are not going to tolerate very much boost. An alternative might be a centrifugal charger running about 4-6 psi maximum. Blow through a proper carb and you will get a reasonable cooling effect that might allow the 4-6 psi boost. If you also use an intercooler then the boosted charge will be nice and cool and the higher CR will less likely lead to problems. The bottom end is another story. They put blow through centrifugals on street cars with relatively high CR's commonly.

I'm considering one for my 502 with 9.6:1 CR. But I am also considering putting some larger heads on it to knock the CR down to 9:1 first.

Kitz