Wide LSA cams broaden the torque range with a flatter torque curve for a longer period where narrow LSA produce more power but in a on/off torque band. Duration determines the operating range of a cam and ICL determines more of the CR the cam will give.

300 adv. duration 260 @.050 106 LSA Installed 106 will have close to the same effective compression as a 300 adv. duration 260 @.050 112 LSA intalled 106 intake centerline. The 106 will make more power but the 112 will have a broader power curve. The wider LSA will idle better but will be down on hp/torque. As Pat pointed out, when cams get really big the LSA has to widen because of overlap. Blowers and Nitrous applications need the wide LSA to blow the cylinder down. On a wide LSA cam, the exhaust opens sooner. This can hurt a N/A engine by allowing usable cylinder pressure to bleed off too soon. By using a large cam with a low CR, you don't really gain much performance, but it will push the power band way up into the rpm range. Best performance comes by matching the cam to the CR.

Here is a calculator you can use to see the effective cr with a given cam and Intake centerline. www.zonk.com/crcalc.htm