Bob, TechInspector is right, you have to know your actual c/r before you move any further, anything else would be just guessing, and that's no good. Those heads are pretty good for GM heads, Im using them on my 505. But they're pretty large intake runners (325cc), making them a better high rpm head...not to say they wont work OK on the street, but you might give up a little torque with a 427. They are 107cc (maybe 108) in chamber size, so you can get a decent c/r with flat top pistons (maybe 9/1) depending on the other variables mentioned. I personally would go with a solid lifter cam, but that's just me. Some people dont like the noisy clatter (its not that bad). Dont let anyone tell you that you have to adjust solid lifters all the time, once they're set and run for awhile, you just set them maybe once a year. A solid cam will rev higher than a hydraulic. Im basing this on your heads alone. Is this strictly a street car? Cam will probably come out to be somewhere around 230 or so duration at .050, and around .540 or .550 lift. (Flat tappet cam) 110 LSA is good, 112 would be a little smoother idle. I would dump the intake, the aftermarket intakes have come a long way over the GM ones from years ago. Maybe a nice Performer RPM or Air Gap. Carb is good. Gears are good for general driving, but I would lean to a bigger stall. That 2200 will also limit your cam choice. My current stall is 3200, and it's fine on the street. (I run a cooler also) Thats gonna be one killer Buick. You have some research to do. Go with a smaller cam company for good info, the bigger ones will only suggest something out of the catalog. Try Howard's Cams, 920-233-5228. Keep us posted on your progress. John