We'd need quite a bit more information to even hazard anything more than a rough guess.

Pump or outdrive? What impeller trim (AA, A, B, etc [no, not bra sizes]) if a pump? If outdrive then type, pitch, wheel dia, cup, single or dual prop?

Ford or Chevy? Not much impact but good to know. What is a "full race cam", what cam grind or at least lift/duration numbers? What compression ratio, what heads, etc?

Size of boat and displacement?

What carburetion are you running right now - you need to establish a baseline - manifold type, CFM, etc?

What RPM at full throttle with the existing setup, how quick before the hull dries out? What is the engines design redline?

How is the boat used - does the wife or girlfriend operate it as well as you so it needs good idle and low RPM qualities? (Not being sexist, I have experienced this firsthand)

Lacking any other information a pair of 600 vac sec Holleys would work just fine for all around play work. Thought about an EFI setup instead?

Regards, Mark