On a street car, a line extended through the crankshaft and a line extended through the pinion should be parallel. The pinion or the engine (or both) need to be offset horizontally or vertically (or both) enough to give about a 3 degree angle between those centerlines and the driveshaft.

I guess you're asking whether you need any vertical angle if you have a good 3* angle to the side. The answer is no.