A 1940 Chev pickup axle will steer all right if it's in good shape. New king pins will usually fix a straight axle. '49-'54 Chev car brakes and hubs fit, giving you 5-bolt wheels.
The S10 frame will fit inside the body, I think, but the front wheels are too far back to get the look I think you're after. The engine is between the front wheels, rather than being mostly behind them like most rods. Plus it's butt ugly.