That is a general question. But I will try to help you out.
Depending on what year it is and what vehical you are installing it in. If it is a pre 1973 and in a light weight car then if properly tuned then should be no problem. Just remember that if it is a pre 1973 then the heads DO NOT have hardend valve seats and some will need to installed or after market heads installed. The unleaded gas you buy now will "eat" the valve seats and let gas/ exhaust back into the head. Also what tranny you using and rear end gears used as well. In genaral you should have no problem smoking the rubber off.
DCON