Those heads have a 75 cc combustion chamber, so if you're going to operate on pump gasoline, you'll have to install pistons with a reverse dome (dish) to get the static compression ratio down to where the motor will not ping. They also have fairly large 310 cc intake runners, so they will operate better in the higher rpm ranges where the speed of the motor will keep the mixture velocity high for good cylinder packing.

Edelbrock also makes a part number 60669 head for the 429/460 which features 95 cc chambers so that you can run flat-top pistons and 292 cc intake runners so that you don't have to buzz the motor so high to keep velocity up.

Your choice.