As mentioned by several members the short answer is yes……but there is a bit more to it than that. It’s obviously not going to be a bolt in.

Chances are you’re going to run into more than an issue or 2 doing it. The motor mounts will have to be custom fabricated as to a certain extent will the exhaust. Chances are you will run into oil pan sump problems (possibly requiring a custom pan due to the center sump design of most MOPAR engines). Then there will be a custom trans mount/crossmember, custom drive shaft, Power Steering connections, transmission shifter and a bit of electrical changes. Depending on the year on and original power plant you may have to look at upgrading brakes and rear end (even into the late 60s some of the A bodies were using the small 5 on 4” bolt pattern).

If you have time and patience, fabrication skills along with an engine hoist, set of tools, welder and a place to work sure it’s doable. If you’re farming out the work it’s not going to be cheap to have it done right.

In the end you’re hopefully very happy with it and have a thick skin as it will not be accepted well by either the Chevy or Mopar camps (the Ford guys will just laugh).

Believe it or not I’m not trying to discourage you, just giving some insight into what to expect.