If it's a new or undisturbed carb, leave it alone until you get the bugs worked out of the car.

Jetting is adjusting the air/fuel ratio for the altitude you drive at and also for the type of driving you do.

Take a look here for some further info:
http://www.edelbrock.com/automotive/eps_intro.html

Pretty much all you need to know about Edelbrock carbs.